| 產(chǎn)品編號 | bs-21283R |
| 英文名稱 | SLC39A13 Rabbit pAb |
| 中文名稱 | 溶質(zhì)載體轉(zhuǎn)運蛋白家族39成員A13抗體 |
| 別 名 | FLJ25785; LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; S39AD_HUMAN; SLC39A13; solute carrier family 39(metal ion transporter), member 13; solute carrier family 39(zinc transporter), member 13; Solute carrier family 39 member 13; Zinc transporter ZIP13; ZIP-13; Zrt-and Irt-like protein 13. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | Mouse,Rat (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC39A13: 1-100/371 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the LIV-1 subfamily of the ZIP transporter family. The encoded transmembrane protein functions as a zinc transporter. Mutations in this gene have been associated with the spondylocheiro dysplastic form of Ehlers-Danlos syndrome.[provided by RefSeq, Mar 2010] Function: Acts as a zinc-influx transporter. Subcellular Location: Membrane. DISEASE: Defects in SLC39A13 are the cause of Ehlers-Danlos syndrome-like spondylocheirodysplasia (SCD-EDS) [MIM:612350]. SCD-EDS is a 'spondylocheiro dysplastic form of Ehlers-Danlos syndrome'. The syndrome consists of a generalized skeletal dysplasia involving mainly the spine (spondylo) and striking clinical abnormalities of the hands (cheiro) in addition to the EDS-like features. Clinical features included postnatal growth retardation, moderate short stature, protuberant eyes with bluish sclerae, hands with finely wrinkled palms, atrophy of the thenar muscles, and tapering fingers. Patients have thin, hyperelastic skin and hypermobile small joints consistent with an Ehlers-Danlos-like phenotype. Radiologic features included mild to moderate platyspondyly, mild to moderate osteopenia of the spine, small ileum, flat proximal femoral epiphyses, short, wide femoral necks, and broad metaphyses (elbows, knees, wrists, and interphalangeal joints). Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. SWISS: Q96H72 Gene ID: 91252 Database links: Entrez Gene: 743682 Chimpanzee Entrez Gene: 91252 Human Entrez Gene: 68427 Mouse Entrez Gene: 713420 Rhesus monkey Omim: 608735 Human SwissProt: Q96H72 Human SwissProt: Q8BZH0 Mouse Unigene: 523664 Human Unigene: 192375 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Skin tissue lysates
Lane 2: Rat Skin tissue lysates
Primary: Anti-SLC39A13 (bs-21283R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kDa
Observed band size: 42 kDa
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