| 產(chǎn)品編號 | bs-11203R-BF488 |
| 英文名稱 | Rabbit Anti-OCT6/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的八聚體結(jié)合轉(zhuǎn)錄因子6抗體 |
| 別 名 | transcription factor 1; OCT 6; OCT 6; OCT-6; OCT-6; OCT6; OCT6; Octamer-binding protein 6; Octamer-binding transcription factor 6; OTF-6; OTF6; OTF6; PO3F1_HUMAN; POU class 3 homeobox 1; POU domain; POU domain class 3 transcription factor 1; POU domain class 3 transcription factor 1; POU domain transcription factor SCIP; POU-domain transcription factor SCIP; POU3F1; POU3F1; scip (gene name); SCIP. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 干細(xì)胞 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OCT6 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the organic zwitterions transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]. Function: High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Cell membrane. Note=Detected in the plasma mebrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. Tissue Specificity: Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34(+) leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. Similarity: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. Database links: Entrez Gene: 5453 Human Entrez Gene: 18991 Mouse Omim: 602479 Human SwissProt: Q03052 Human SwissProt: P21952 Mouse Unigene: 1837 Human Unigene: 297371 Mouse Unigene: 82720 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
